Photoprotective Efficacy of the Association of Rosmarinic Acid 0.1% with Ethylhexyl Methoxycinnamate and Avobenzone

Innovative prototype sunscreens with reduced ultraviolet (UV) filters are required to achieve safer, more effective, and environmentally friendly formulations. Rosmarinic acid (RA) is a phenolic antioxidant potential candidate for multifunctional sunscreens. We used RA (0.1% w/w) in combination avobenzone (2.5% 5.0% w/w), UVA filter, ethylhexyl methoxycinnamate (10.0% UVB evaluate vitro sun protection factor (SPF) critical wavelength, photostability, the vivo SPF. RA, vitro, improved SPF of F2 (ethylhexyl 10.0% w/w + 2.5% 0.1% F3 which also presented broad-spectrum profiles; however, no expressive effects were observed wavelength (nm). By trial, showed an increment value maintained effectiveness, even when was at 2.5%. Nonetheless, increase photostability observed. Our findings suggest that incorporating natural molecules activities into could decrease proportion conventional UV final product, advantage providing other functional properties. Further investigation higher concentrations, from sources, filter combinations reveal important data development